Potensi Afrodisiak Kandungan Aktif Buah Cabe Jawa (Piper retrofractum Vahl) pada Tikus Jantan Galur Wistar
(Aphrodisiac Potency of the Active Constituents of Piper retrofractum Vahl Fruit in Male Wistar Rats)
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Siti Muslichah
Dosen Bagian Biologi Farmasi, Universitas Jember, Jember, Indonesia
DOI:
ABSTRACT
Java long pepper (Piper retrofractum Vahl) is one of the Indonesian original plants having aphrodisiac activity. This study was aimed to isolate piperine and to evaluate aphrodisiac potency of piperine and piperine-free insoluble n-hexane fraction from ethanolic extract of P. retrofractum. Twenty five male rats were randomized into 5 groups. Oral repeated administration once a day for 27 days were given to andriol group (0.72 mg/day), CMC-Na 1%, piperine (1.6 mg/kg body weight), piperine-free insoluble n-hexane fraction (2.1 mg/kg body weight), insoluble n-hexane fraction (31.72 mg/kg body weight). Rat’s sexual behavior including sexual introduction and climbing were observed in day 0, 1, 3, 5, 7, 11, 15, 19, 23, and 27. Normal and homogenous data were analyzed statistically with one-way ANOVA, followed by LSD test. The result showed that the administration of andriol, piperine, piperine-free insoluble n-hexane fraction, and total insoluble n-hexane fraction has a significant increase in the frequency of introduction, compared to the group of CMC-Na 1% (p<0.05). There was also a significant increase of piperine and piperine- free insoluble n-hexane fraction in the frequency of climbing (p<0.05).
Keywords: Piper retrofractum Vahl, sexual behavior, piperine, aphrodisiac
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Published
20-12-2011
Issue
Vol. 5 No. 2 2011: Jurnal Agroteknologi
Pages
11-20
License
Copyright (c) 2011 Jurnal Agroteknologi
How to Cite
Muslichah, S. (2011). Potensi afrodisiak kandungan aktif buah cabe jawa (Piper retrofractum Vahl) pada tikus jantan galur wistar. Jurnal Agroteknologi, 5(2), 11-20.
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